Description

trans-4-Hydroxy-4-Methylcyclohexanecarboxylic Acid is a versatile chiral building block and intermediate characterized by its hydroxyl and carboxylic acid functional groups on a substituted cyclohexane ring. This compound is valued for its role in the synthesis of complex molecules, particularly in the pharmaceutical and fine chemical industries, where precise stereochemistry is critical. It serves as a key precursor for researchers and manufacturers developing active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific stereochemical configurations for enhanced efficacy.
• Fine Chemical Production: Serves as a building block for fragrances, flavors, and specialty chemicals where the trans- configuration imparts desired physical and olfactory properties.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers and liquid crystal materials for electronic displays.
• Asymmetric Catalysis & Ligand Development: Employed in the research and development of chiral catalysts and ligands for stereoselective synthesis.
• Academic & R&D Laboratories: Used in chemical research for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Item	Detail
Product Name	trans-4-Hydroxy-4-Methylcyclohexanecarboxylic Acid
CAS No.	937-28-0
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	trans-4-Hydroxy-4-methylcyclohexanecarboxylic acid; (1r,4r)-4-Hydroxy-4-methylcyclohexanecarboxylic acid; 4-Methyl-4-hydroxycyclohexanecarboxylic acid (trans); 4-Hydroxy-4-methylcyclohexanecarboxylic acid, trans-; 4-Methyl-4-hydroxycyclohexane-1-carboxylic acid; NSC 403697; p-Hydroxy-p-methylcyclohexanecarboxylic acid
EINECS	Contact for details

Quality Control

Our trans-4-Hydroxy-4-Methylcyclohexanecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm the trans- configuration, and standard identification tests. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided to ensure compliance with your specific R&D or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% trans- isomer
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.