Description

Thioacetic Acid S-(3-Bromopropyl) Ester is a versatile sulfur-containing organic building block characterized by its reactive thioester and bromoalkyl functionalities. This compound is essential for introducing the 3-mercaptopropyl moiety into target molecules, serving as a key intermediate in sophisticated synthetic pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor for the synthesis of drug candidates, particularly those containing thiol or disulfide linkages, and for prodrug strategies.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the thiol group is incorporated for biological activity.
• Polymer Modification & Functionalization: Employed to introduce thiol groups onto polymer backbones or surfaces for creating cross-linked networks, adhesives, or smart materials.
• Bioconjugation & Linker Chemistry: Acts as a heterobifunctional reagent for coupling biomolecules (e.g., peptides, proteins) to other entities like dyes, drugs, or solid supports.
• Ligand Synthesis for Catalysis: Serves as a starting material for preparing sulfur-based ligands used in transition metal catalysis.
• Organic Synthesis Building Block: Utilized in nucleophilic substitution reactions and as a masked thiol source in multi-step synthetic sequences.

Basic Information

Product Name	Thioacetic Acid S-(3-Bromopropyl) Ester
CAS No.	928-46-1
Molecular Formula	C5H9BrOS
Molecular Weight	197.09 g/mol
Synonyms	3-Bromopropyl thioacetate; S-(3-Bromopropyl) ethanethioate; 1-Bromo-3-(acetylthio)propane; 3-(Acetylthio)propyl bromide; Thioacetic acid, S-(3-bromopropyl) ester; Acetyl 3-bromopropyl sulfide; 3-Bromopropan-1-yl thioacetate
EINECS	Contact for details

Quality Control

Our Thioacetic Acid S-(3-Bromopropyl) Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.