Description

4-tert-Butylcyclohexanone is a versatile alicyclic ketone characterized by its unique sterically hindered structure. This compound is valued as a crucial chiral intermediate and building block in advanced organic synthesis, offering a rigid cyclohexane backbone for constructing complex molecules. It is primarily utilized by research institutions and industrial manufacturers in the fragrance, pharmaceutical, and specialty chemical sectors.

Application

• Fragrance and Flavor Intermediate: Serves as a key precursor in the synthesis of musky and woody aroma chemicals, such as derivatives used in high-end perfumery.
• Pharmaceutical Synthesis: Acts as a chiral building block for the development of active pharmaceutical ingredients (APIs) and other bioactive molecules.
• Organic Synthesis Reagent: Used in various reactions including Grignard additions, reductions, and alkylations to introduce the tert-butylcyclohexyl moiety.
• Liquid Crystal and Polymer Chemistry: Employed as a monomer or intermediate in the production of specialty polymers and materials with specific optical properties.
• Agrochemical Research: Functions as an intermediate in the development of novel crop protection agents and pesticides.
• Catalyst and Ligand Development: Utilized in the design of sterically demanding ligands for asymmetric catalysis.

Basic Information

Product Name	4-tert-Butylcyclohexanone
CAS No.	98-53-3
Molecular Formula	C10H18O
Molecular Weight	154.25 g/mol
Synonyms	p-tert-Butylcyclohexanone; 4-(1,1-Dimethylethyl)cyclohexanone; 4-tert-Butylcyclohexan-1-one; NSC 403697; 4-t-Butylcyclohexanone; 4-(tert-Butyl)cyclohexanone; Cyclohexanone, 4-(1,1-dimethylethyl)-
EINECS	202-680-8

Quality Control

Our 4-tert-Butylcyclohexanone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, enantiomeric purity (where applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates and ISO standards for industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.