Description

Pyridine-2-Carboxaldoxime Methiodide is a specialized quaternary ammonium salt derivative of pyridine-2-carboxaldoxime, widely recognized as a potent reactivator of acetylcholinesterase inhibited by organophosphorus compounds. This compound is critical for research and development in antidotal therapies and serves as a key intermediate in synthetic organic chemistry. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical manufacturers, and academic institutions focused on neuropharmacology and chemical synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of acetylcholinesterase reactivators (oximes) used as antidotes for organophosphate poisoning.
• Biochemical Research: Essential reagent in studies of enzyme kinetics, neurotoxicology, and the mechanism of action of nerve agents.
• Agrochemical Development: Used in the research and synthesis of novel pesticides and their corresponding detoxifying agents.
• Chemical Synthesis: Valuable building block for preparing complex heterocyclic compounds and quaternary ammonium salts with specific biological activity.
• Analytical Chemistry: Employed as a reference standard and reagent in chromatographic analysis and method development for related compounds.

Basic Information

Product Name	Pyridine-2-Carboxaldoxime Methiodide
CAS No.	94-63-3
Molecular Formula	C8H11IN2O
Molecular Weight	278.09 g/mol
Synonyms	2-Pyridinealdoxime Methiodide; Pralidoxime Methiodide; 2-PAM Methiodide; 2-Formylpyridine Oxime Methiodide; 2-Hydroxyiminomethyl-1-methylpyridinium Iodide; 1-Methyl-2-pyridiniumaldoxime Iodide; Pyridine-2-aldoxime Methiodide; Contrathion Methiodide
EINECS	202-350-8

Quality Control

Our Pyridine-2-Carboxaldoxime Methiodide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets high-purity standards for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	218 - 222 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.