Description

3'-Chloro-3-(2,4-Dimethylphenyl)-4'-Fluoropropiophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated aromatic structure. This compound is of significant commercial importance for its role in the synthesis of complex active pharmaceutical ingredients (APIs), where its unique molecular framework serves as a critical building block. It is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries engaged in developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides due to its halogenated aromatic structure.
• Organic Synthesis Research: Serves as a versatile precursor for creating complex molecules in academic and industrial R&D laboratories.
• Ligand and Catalyst Development: Potential use in the preparation of specialized ligands for catalytic processes.
• Material Science Precursor: Can be utilized in the synthesis of organic electronic materials and specialty polymers.

Basic Information

Product Name	3'-Chloro-3-(2,4-Dimethylphenyl)-4'-Fluoropropiophenone
CAS No.	898794-24-6
Molecular Formula	C17H16ClFO
Molecular Weight	290.76 g/mol
Synonyms	1-(3-Chloro-4-fluorophenyl)-3-(2,4-dimethylphenyl)propan-1-one; 3-(2,4-Dimethylphenyl)-1-(3-chloro-4-fluorophenyl)propan-1-one; 3'-Chloro-3-(2,4-dimethylphenyl)-4'-fluoropropiophenone; 898794-24-6; Propiophenone, 3'-chloro-3-(2,4-dimethylphenyl)-4'-fluoro-; 3-(2,4-Dimethylphenyl)-1-(3-chloro-4-fluorophenyl)-1-propanone
EINECS	Contact for details

Quality Control

Our 3'-Chloro-3-(2,4-Dimethylphenyl)-4'-Fluoropropiophenone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support compliance with cGMP and ISO 9001 standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light) and should be handled under an inert atmosphere if prolonged exposure is anticipated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.