Description

6-Chloro-1-(4-Iodophenyl)-1-Oxohexane is a high-purity, halogenated aromatic ketone building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate unique halogenated motifs into their target structures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where the chloro and iodo substituents can contribute to biological activity and binding specificity.
• Ligand and Catalyst Development: Acts as a starting material for creating specialized ligands used in transition metal catalysis and cross-coupling reactions, such as Suzuki or Sonogashira couplings.
• Material Science Precursor: Employed in the synthesis of monomers or additives for advanced polymers and liquid crystals, where the aromatic core and ketone functionality are essential.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying biological pathways, leveraging the iodine atom for potential radiolabeling (with I-125) or as a heavy atom in crystallography.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a gram to kilogram scale.

Basic Information

Product Name	6-Chloro-1-(4-Iodophenyl)-1-Oxohexane
CAS No.	898768-23-5
Molecular Formula	C12H14ClIO
Molecular Weight	336.60 g/mol
Synonyms	6-Chloro-1-(4-iodophenyl)hexan-1-one; 4'-Iodo-6-chlorohexanophenone; 1-(4-Iodophenyl)-6-chloro-1-hexanone; ω-Chloro-4'-iodovalerophenone; 6-Chlorohexanophenone, 4'-iodo-; (4-Iodophenyl) 6-chlorohexyl ketone; 6-Chloro-1-(p-iodophenyl)-1-hexanone
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-(4-Iodophenyl)-1-Oxohexane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and GC for residual solvent analysis, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.