Description

4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-2'-[(4-Trifluoromethyl)Phenyl]Butyrophenone CAS NO 898757-59-0 is a high-purity, advanced pharmaceutical intermediate characterized by its unique dioxane and trifluoromethylphenyl functional groups. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its complex molecular architecture.
• Fine Chemical Synthesis: Serves as a precursor for the preparation of more complex fluorinated organic compounds.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Product Name	4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-2'-[(4-Trifluoromethyl)Phenyl]Butyrophenone
CAS No.	898757-59-0
Molecular Formula	C23H25F3O3
Molecular Weight	406.44 g/mol
Synonyms	4-(5,5-Dimethyl-1,3-dioxan-2-yl)-2'-[4-(trifluoromethyl)phenyl]butyrophenone; 2'-[(4-Trifluoromethyl)Phenyl]-4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Butyrophenone; 898757-59-0; Butyrophenone, 4-(5,5-dimethyl-1,3-dioxan-2-yl)-2'-[4-(trifluoromethyl)phenyl]-; 4-(5,5-Dimethyl-1,3-dioxan-2-yl)-2'-(4-trifluoromethylphenyl)butyrophenone
EINECS	Contact for details

Quality Control

Our 4-(5,5-Dimethyl-1,3-Dioxan-2-Yl)-2'-[(4-Trifluoromethyl)Phenyl]Butyrophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.