Description

2',6'-Dichloro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated and protected ketone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), where its unique scaffold enables precise chemical transformations. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries engaged in developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry research.
• Organic Synthesis Reagent: Used in advanced organic reactions, including cross-coupling and functional group transformations, due to its reactive ketone and protected diol moieties.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for method development and compound library generation.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high structural complexity and purity.

Basic Information

Product Name	2',6'-Dichloro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone
CAS No.	898757-01-2
Molecular Formula	C₁₇H₂₂Cl₂O₃
Molecular Weight	345.26 g/mol
Synonyms	5,5-Dimethyl-2-[5-(2,6-dichlorobenzoyl)pentyl]-1,3-dioxane; 2',6'-Dichloro-5-(5,5-dimethyl-1,3-dioxan-2-yl)valerophenone; 898757-01-2; 2-(5-(2,6-Dichlorobenzoyl)pentyl)-5,5-dimethyl-1,3-dioxane; Valerophenone, 2',6'-dichloro-5-(5,5-dimethyl-1,3-dioxan-2-yl)-
EINECS	Contact for details

Quality Control

Our 2',6'-Dichloro-5-(5,5-Dimethyl-1,3-Dioxan-2-Yl)Valerophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.