Description

Potassium Propargyloxymethyltrifluoroborate is a high-value organotrifluoroborate salt, a versatile building block in modern synthetic chemistry. Its core value lies in enabling efficient and selective cross-coupling reactions, crucial for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and specialty chemical synthesis.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key boron reagent for forming carbon-carbon bonds under mild conditions, widely used in pharmaceutical intermediate synthesis.
• Pharmaceutical Research & Development: Serves as a critical building block for creating novel active pharmaceutical ingredients (APIs) and candidate drug molecules.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with complex structures.
• Material Science: Facilitates the synthesis of conjugated polymers and organic electronic materials for OLEDs and semiconductors.
• Chemical Biology & Probe Development: Enables the site-specific labeling and modification of biomolecules due to its bioorthogonal reactivity.
• Process Chemistry & Scale-up: Provides a stable and handleable alternative to sensitive boronic acids in large-scale manufacturing processes.

Basic Information

Product Name	Potassium Propargyloxymethyltrifluoroborate
CAS No.	898544-65-5
Molecular Formula	C5H5BF3KO
Molecular Weight	187.99 g/mol
Synonyms	Potassium (Prop-2-yn-1-yloxymethyl)trifluoroborate; Potassium Trifluoro(prop-2-yn-1-yloxymethyl)borate; Propargyloxymethyltrifluoroborate Potassium Salt; Potassium (Propargyloxymethyl)trifluoroboronate; K-OTfBM-Propargyl; K/Propargyloxymethyl-Trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium Propargyloxymethyltrifluoroborate is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot undergoes comprehensive analysis, including NMR (1H, 11B, 19F) and HPLC, to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) documenting full specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) to maintain stability and prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
11B NMR Purity	≥ 97%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.