Description

2,4-Bis(Benzyloxy)-5-Bromobenzaldehyde is a high-purity, multi-functional aromatic aldehyde derivative, serving as a critical advanced intermediate in modern organic synthesis. Its value lies in the strategic placement of bromine and benzyl-protected hydroxyl groups, which enable precise, sequential functionalization for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty materials sectors who require reliable building blocks for drug discovery, ligand synthesis, and the development of functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and CNS drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and fungicides, leveraging its halogenated aromatic core.
• Ligand & Catalyst Precursor: Serves as a precursor for sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and photoactive polymers.
• Custom Chemical Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in university laboratories for methodological studies in cross-coupling reactions and protective group chemistry.

Basic Information

Product Name	2,4-Bis(Benzyloxy)-5-Bromobenzaldehyde
CAS No.	898538-49-3
Molecular Formula	C21H17BrO3
Molecular Weight	397.27 g/mol
Synonyms	5-Bromo-2,4-bis(benzyloxy)benzaldehyde; 2,4-Di-O-benzyl-5-bromobenzaldehyde; Benzaldehyde, 5-bromo-2,4-bis(phenylmethoxy)-; 898538-49-3; 5-Bromo-2,4-di(benzyloxy)benzaldehyde; 2,4-Bis(phenylmethoxy)-5-bromobenzaldehyde
EINECS	Contact for details

Quality Control

Every batch of 2,4-Bis(Benzyloxy)-5-Bromobenzaldehyde is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with detailed impurity profiling available. A Certificate of Analysis (COA) documenting all test results is provided with each shipment. We support cGMP standards for pharmaceutical applications and can tailor specifications to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.