Description

1-(4-Fluorophenyl)-n-(5-Methyl-1,3,4-Thiadiazol-2-Yl)-4-Oxo-1,4-Dihydro-3-Pyridazinecarboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally complex building block essential for modern drug discovery programs, particularly in developing targeted therapies. It is primarily needed by research institutions, contract research organizations (CROs), and pharmaceutical companies engaged in the development of new chemical entities, especially within oncology and anti-inflammatory research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel, high-value active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Contract Manufacturing: Supplied to CDMOs for the scale-up and cGMP production of investigational new drugs.
• Oncology Research: Serves as a precursor in the development of targeted kinase inhibitors and other anticancer agents.
• Anti-inflammatory Agent Development: Explored for the creation of new compounds targeting inflammatory pathways.
• Biochemical Research: Utilized as a reference standard or probe in biochemical and pharmacological assays.

Basic Information

Item	Details
Product Name	1-(4-Fluorophenyl)-n-(5-Methyl-1,3,4-Thiadiazol-2-Yl)-4-Oxo-1,4-Dihydro-3-Pyridazinecarboxamide
CAS No.	895841-33-5
Molecular Formula	C15H10FN5O2S
Molecular Weight	343.34 g/mol
Synonyms	1-(4-Fluorophenyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-oxo-1,4-dihydropyridazine-3-carboxamide; 4-Oxo-1-(4-fluorophenyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-1,4-dihydro-3-pyridazinecarboxamide; 1-(4-Fluorophenyl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-4-oxo-1,4-dihydro-3-pyridazinecarboxamide; 3-Pyridazinecarboxamide, 1-(4-fluorophenyl)-1,4-dihydro-4-oxo-N-(5-methyl-1,3,4-thiadiazol-2-yl)-; CAS 895841-33-5
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorophenyl)-n-(5-Methyl-1,3,4-Thiadiazol-2-Yl)-4-Oxo-1,4-Dihydro-3-Pyridazinecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with exacting standards for pharmaceutical research. Certificates of Analysis (COA) with full traceability are available upon request, and custom purity grades can be supplied to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.