Description

2H-Pyran-4-Carboxylic Acid, 4-(4-Bromophenyl)Tetrahydro-, Methyl Ester is a specialized brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by research chemists and process development scientists working on novel active ingredients, where its unique fused pyran structure and bromine substituent offer valuable synthetic handles for further functionalization.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its bromophenyl moiety for bioactivity.
• Material Science Precursor: Serves as a monomer or precursor for specialty polymers and advanced organic materials with specific optical or electronic properties.
• Chemical Biology Probe Synthesis: Employed in creating molecular probes for studying enzyme function and biological pathways.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces.
• Fine Chemical Synthesis: Acts as a versatile intermediate for constructing complex natural product analogs and other high-value fine chemicals.

Basic Information

Product Name	2H-Pyran-4-Carboxylic Acid, 4-(4-Bromophenyl)Tetrahydro-, Methyl Ester
CAS No.	894399-90-7
Molecular Formula	C13H15BrO3
Molecular Weight	299.16 g/mol
Synonyms	Methyl 4-(4-bromophenyl)tetrahydro-2H-pyran-4-carboxylate; 4-(4-Bromophenyl)tetrahydro-2H-pyran-4-carboxylic acid methyl ester; Tetrahydro-2H-pyran-4-carboxylic acid, 4-(4-bromophenyl)-, methyl ester; 894399-90-7; Methyl 4-(p-bromophenyl)tetrahydro-2H-pyran-4-carboxylate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We provide material with typical purity grades suitable for research and development, supported by comprehensive analytical data. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request for every batch, ensuring traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Research Grade)
Purity (HPLC)	≥ 98% (Premium Grade)
Melting Point	Contact for details
Loss on Drying	< 0.5%
Residue on Ignition	< 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.