Description

2,5,6,7-Tetrahydro-2-Thioxo-4-(Trifluoromethyl)-1H-Cyclopenta[B]-Pyridine-3-Carbonitrile is a high-value, heterocyclic organic compound featuring a fused cyclopentapyridine core with a thioxo group and a strategically positioned trifluoromethyl substituent. This unique molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients targeting a range of therapeutic and crop protection applications.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammatory diseases, and metabolic conditions.
• Agrochemical Research: Used as a sophisticated building block for developing new-generation herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the trifluoromethyl group.
• Medicinal Chemistry & Drug Discovery: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in high-throughput screening campaigns.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes to study enzyme function and biological pathways.
• Organic Synthesis Research: Used in academic and industrial laboratories to explore novel heterocyclic reactions and develop new synthetic methodologies.

Basic Information

Product Name	2,5,6,7-Tetrahydro-2-Thioxo-4-(Trifluoromethyl)-1H-Cyclopenta[B]-Pyridine-3-Carbonitrile
CAS No.	893757-46-5
Molecular Formula	C10H7F3N2S
Molecular Weight	244.24 g/mol
Synonyms	4-(Trifluoromethyl)-2-thioxo-1,2,5,6,7,8-hexahydrocyclopenta[b]pyridine-3-carbonitrile; 2-Thioxo-4-(trifluoromethyl)-1,2,5,6,7,8-hexahydrocyclopenta[b]pyridine-3-carbonitrile; Cyclopenta[b]pyridine-3-carbonitrile, 2,5,6,7-tetrahydro-2-thioxo-4-(trifluoromethyl)-1H-; 893757-46-5; CAS 893757-46-5
EINECS	Contact for details

Quality Control

Our production of 2,5,6,7-Tetrahydro-2-Thioxo-4-(Trifluoromethyl)-1H-Cyclopenta[B]-Pyridine-3-Carbonitrile adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical specifications. Our quality system is designed to support cGMP compliance for pharmaceutical applications, ensuring traceability and reliability for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.