Description

3,5-Difluoro-4-Methoxybenzeneboronic Acid Pinacol Ester, 96% is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and the development of novel functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl halides and this boronic ester, fundamental in synthesizing biaryl structures.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing difluoromethoxy-substituted aromatic rings.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Organic Light-Emitting Diodes (OLEDs): A building block for electron-transport materials and emissive layer components in display technologies.
• Polymer and Advanced Material Science: Incorporated into monomers for creating high-performance polymers with specific thermal and chemical resistance properties.

Basic Information

Product Name	3,5-Difluoro-4-Methoxybenzeneboronic Acid Pinacol Ester, 96%
CAS No.	890839-37-9
Molecular Formula	C14H19BF2O3
Molecular Weight	284.11 g/mol
Synonyms	3,5-Difluoro-4-methoxyphenylboronic acid pinacol ester; (3,5-Difluoro-4-methoxyphenyl)boronic acid pinacol ester; 4-Methoxy-3,5-difluorobenzeneboronic acid pinacol ester; Pinacol (3,5-difluoro-4-methoxyphenyl)boronate; B-(3,5-Difluoro-4-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 3,5-Difluoro-4-methoxybenzeneboronic acid, pinacol cyclic ester; Boronic acid, B-(3,5-difluoro-4-methoxyphenyl)-, cyclic ester with pinacol
EINECS	Contact for details

Quality Control

Our 3,5-Difluoro-4-Methoxybenzeneboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and GC to verify identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 96.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.