Description

3-[(Benzyloxy)Methyl]-2-Fluorocyclobutan-1-One is a high-value fluorinated cyclobutanone derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring a fluorine atom and a benzyl-protected hydroxymethyl group, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Building block for novel herbicides and pesticides, where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Used in the development of specialty polymers and liquid crystals, leveraging the cyclobutanone core for rigidity.
• Chemical Synthesis: Versatile electrophile and scaffold in medicinal chemistry for constructing spirocyclic and fused ring systems.
• Fluorine Chemistry: A valuable reagent for studying structure-activity relationships (SAR) in fluorinated compound libraries.

Basic Information

Product Name	3-[(Benzyloxy)Methyl]-2-Fluorocyclobutan-1-One
CAS No.	890529-23-4
Molecular Formula	C12H13FO2
Molecular Weight	208.23 g/mol
Synonyms	2-Fluoro-3-(benzyloxymethyl)cyclobutan-1-one; 2-Fluoro-3-(phenylmethoxymethyl)cyclobutanone; 3-(Benzyloxymethyl)-2-fluorocyclobutanone; 890529-23-4; 2-Fluorocyclobutan-1-one, 3-[(benzyloxy)methyl]-; Benzyl 2-fluoro-3-oxocyclobutylmethyl ether
EINECS	Contact for details

Quality Control

Our production of 3-[(Benzyloxy)Methyl]-2-Fluorocyclobutan-1-One adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.