Description

2-(Tetrahydro-Pyran-2-Ylmethoxy)-Phenylamine is a specialized aromatic amine derivative featuring a tetrahydropyran-protected methoxy group, which serves as a key synthetic intermediate in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting CNS disorders or inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, or plant growth regulators where its amine functionality is key.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of dyes, pigments, and advanced electronic chemicals.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis, including cross-coupling and protection/deprotection strategies.
• Polymer Modification: Can be used to introduce amine functionality into polymer backbones for creating specialty polymers with tailored properties.

Basic Information

Product Name	2-(Tetrahydro-Pyran-2-Ylmethoxy)-Phenylamine
CAS No.	889940-08-3
Molecular Formula	C₁₂H₁₇NO₂
Molecular Weight	207.27 g/mol
Synonyms	2-[(Tetrahydro-2H-pyran-2-yl)oxy]aniline; 2-(THP-O-Methoxy)aniline; 2-Aminophenyl THP methyl ether; 2-(Tetrahydro-2H-pyran-2-ylmethoxy)benzenamine; 2-(THPOM)Aniline; 2-(2-Tetrahydropyranylmethoxy)phenylamine; Benzenamine, 2-[(tetrahydro-2H-pyran-2-yl)oxy]-; 889940-08-3
EINECS	Contact for details

Quality Control

Our 2-(Tetrahydro-Pyran-2-Ylmethoxy)-Phenylamine is produced under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting purity, assay, and impurity profiles. Our quality commitment aligns with cGMP and ISO 9001 principles where applicable, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider using an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Light yellow to amber liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.