Description

4-(2-Fluoro-Phenyl)-Tetrahydro-Pyran-4-Carboxylic Acid is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its unique structural motif, which combines a fluorinated aromatic ring with a tetrahydro-pyran carboxylic acid group, enabling precise molecular modifications. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atom and heterocyclic structure can enhance biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty monomers or ligands in the creation of functional polymers and advanced catalytic systems.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	4-(2-Fluoro-Phenyl)-Tetrahydro-Pyran-4-Carboxylic Acid
CAS No.	889939-77-9
Molecular Formula	C13H15FO3
Molecular Weight	238.26 g/mol
Synonyms	4-(2-Fluorophenyl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(2-Fluorophenyl)oxane-4-carboxylic acid; 2-Fluoro-α,α-pentamethylenebenzenepropanoic acid; 4-Carboxy-4-(2-fluorophenyl)tetrahydropyran; 889939-77-9; 4-(2-Fluorophenyl)-4-carboxytetrahydropyran; 4-(2-Fluorophenyl)tetrahydropyran-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-(2-Fluoro-Phenyl)-Tetrahydro-Pyran-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.