Description

5-Chloro-2-Methoxy-4-Methylbenzenesulfonyl Chloride is a high-purity, multi-functional sulfonyl chloride derivative essential for advanced organic synthesis. This compound serves as a critical building block for introducing the sulfonyl functional group, enabling the creation of complex molecules with tailored properties. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the sulfonyl moiety is required for bioactivity.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialty dyes and colorants.
• Polymer Chemistry: Employed as a modifying agent or cross-linking monomer in the synthesis of specialty polymers and resins.
• Chemical Research: A versatile reagent in academic and industrial R&D for exploring new synthetic pathways and creating molecular libraries.
• Ligand and Catalyst Development: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	5-Chloro-2-Methoxy-4-Methylbenzenesulfonyl Chloride
CAS No.	889939-48-4
Molecular Formula	C8H8Cl2O3S
Molecular Weight	255.12 g/mol
Synonyms	4-Methyl-5-chloro-2-methoxybenzenesulfonyl chloride; 2-Methoxy-4-methyl-5-chlorobenzenesulfonyl chloride; 5-Chloro-2-methoxy-p-toluenesulfonyl chloride; 1-Chloro-4-methoxy-2-methyl-5-sulfonyl chloride benzene; Benzenesulfonyl chloride, 5-chloro-2-methoxy-4-methyl-; CAS 889939-48-4
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methoxy-4-Methylbenzenesulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and reliability for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.