Description

2-Chloro-5-(Tributylstannyl)-1,3-Thiazole is a high-value organotin intermediate, specifically a stannylated heterocyclic compound, with the CAS registry number 889672-73-5. This compound is critical for its role in facilitating Stille cross-coupling reactions, a cornerstone methodology in modern synthetic organic chemistry for forming carbon-carbon bonds. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and efficient synthetic pathways.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of complex drug candidates, particularly those containing thiazole or other heterocyclic cores, via Stille coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require the introduction of the 2-chlorothiazole moiety.
• Material Science Research: Building block for creating functionalized polymers, organic semiconductors, and liquid crystalline materials through palladium-catalyzed reactions.
• Chemical Synthesis: Versatile organometallic reagent for academic and industrial R&D labs performing cross-coupling chemistry to construct complex molecular architectures.
• Ligand Precursor: Can serve as a starting material for the development of novel organotin catalysts or ligands in coordination chemistry.

Basic Information

Item	Detail
Product Name	2-Chloro-5-(Tributylstannyl)-1,3-Thiazole
CAS No.	889672-73-5
Molecular Formula	C15H28ClNSn
Molecular Weight	392.59 g/mol
Synonyms	5-(Tributylstannyl)-2-chlorothiazole; 2-Chloro-5-(tributylstannyl)thiazole; Tributyl(2-chloro-1,3-thiazol-5-yl)stannane; 2-Chlorothiazole-5-tributyltin; Stannane, tributyl(2-chloro-5-thiazolyl)-; (2-Chloro-1,3-thiazol-5-yl)tributylstannane
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-5-(Tributylstannyl)-1,3-Thiazole is produced and analyzed under strict quality management protocols. We guarantee high chemical purity and consistency, supported by comprehensive analytical data including NMR (¹H, ¹³C), HPLC, and GC analysis. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure it meets the rigorous standards required for advanced synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label or COA. This compound is easily oxidized and light-sensitive. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 95% (Typical 97-99%)
Tin (Sn) Content	~30.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.