Description

Potassium Trifluoro[(Pyrrolidin-1-Yl)Methyl]Borate is a specialized organoboron reagent featuring a trifluoroborate moiety linked to a pyrrolidine-derived substituent. This compound is valued for its enhanced stability and solubility in organic solvents compared to traditional boronic acids, making it a crucial building block in modern synthetic chemistry. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for advanced cross-coupling reactions and the development of novel active ingredients.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: As a stable organotrifluoroborate reagent for the efficient formation of carbon-carbon bonds in complex molecule synthesis.
• Pharmaceutical Intermediate Synthesis: For constructing key molecular scaffolds in the research and development of new drug candidates.
• Agrochemical Active Ingredient Development: Used in the synthesis of novel herbicides, fungicides, and insecticides.
• Material Science Research: As a precursor for creating boron-containing polymers or advanced organic electronic materials.
• Medicinal Chemistry Library Construction: Enabling high-throughput synthesis of diverse compound libraries for biological screening.
• Catalyst and Ligand Development: Serving as a building block for novel chiral ligands or metal-organic frameworks (MOFs).

Basic Information

Product Name	Potassium Trifluoro[(Pyrrolidin-1-Yl)Methyl]Borate
CAS No.	888711-53-3
Molecular Formula	C5H10BF3KN
Molecular Weight	185.05 g/mol
Synonyms	Potassium (Pyrrolidin-1-ylmethyl)trifluoroborate; Potassium Trifluoro(pyrrolidin-1-ylmethyl)borate; (Pyrrolidin-1-ylmethyl)trifluoroborate Potassium Salt; 1-(Trifluoroboratomethyl)pyrrolidine Potassium Salt; N-(Trifluoroboratomethyl)pyrrolidine Potassium Salt; Potassium N-(Trifluoroboratomethyl)pyrrolidinide
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro[(Pyrrolidin-1-Yl)Methyl]Borate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 13C) and HPLC analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in GLP and cGMP environments where traceability and consistency are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator to prevent decomposition. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.