Description

Potassium n-Cyclohexyl-Aminomethyltrifluoroborate is a specialized organotrifluoroborate salt, a valuable class of reagents in modern synthetic chemistry. Its primary value lies in its enhanced stability and handling characteristics compared to traditional boronic acids, making it a crucial building block for cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A stable and efficient alternative to boronic acids for forming carbon-carbon bonds, particularly in complex molecule synthesis.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), enabling the introduction of cyclohexylamino-methyl motifs.
• Agrochemical Compound Development: Serves as a key precursor in creating novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Employed in the synthesis of organic electronic materials, ligands for catalysts, and other functional organic molecules.
• Peptide Modification and Bioconjugation: Facilitates the site-specific labeling or functionalization of biomolecules due to its selective reactivity.
• Library Synthesis for Drug Discovery: A valuable reagent in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	Potassium n-Cyclohexyl-Aminomethyltrifluoroborate
CAS No.	888711-52-2
Molecular Formula	C7H14BF3KN
Molecular Weight	225.10 g/mol
Synonyms	Potassium (Cyclohexylaminomethyl)trifluoroborate; Potassium Cyclohexylaminomethyl-Trifluoroborate; n-Cyclohexylaminomethyltrifluoroborate Potassium Salt; (Aminomethylcyclohexane)Trifluoroborate Potassium Salt; Potassium Trifluoro((cyclohexylamino)methyl)borate; K-CHAT
EINECS	Contact for details

Quality Control

Our Potassium n-Cyclohexyl-Aminomethyltrifluoroborate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B, ¹⁹F) for structural confirmation and HPLC for purity assessment, to ensure consistency and compliance with high-grade chemical standards. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
¹¹B NMR Purity	≥ 97%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.