Description

n-(4-Tetrahydropyranylmethyl)Benzylamine is a versatile amine-protected intermediate of significant importance in advanced organic synthesis. Its primary value lies in its role as a key building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists working on new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those requiring protected amine functionalities.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
• Peptidomimetics and Bioactive Molecules: Employed in the construction of peptide analogs and other biologically active compounds where the tetrahydropyranyl (THP) group acts as a protective moiety.
• Material Science Research: Utilized as a monomer or functionalizing agent in the development of specialty polymers and advanced materials.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis projects in CDMO (Contract Development and Manufacturing Organization) facilities.

Basic Information

Product Name	n-(4-Tetrahydropyranylmethyl)Benzylamine
CAS No.	887978-20-3
Molecular Formula	C13H19NO
Molecular Weight	205.30 g/mol
Synonyms	N-[(Tetrahydro-2H-pyran-4-yl)methyl]-1-phenylmethanamine; 1-Phenyl-N-[(tetrahydro-2H-pyran-4-yl)methyl]methanamine; Benzyl(tetrahydro-2H-pyran-4-ylmethyl)amine; N-Benzyl-1-(tetrahydro-2H-pyran-4-yl)methanamine; N-(4-Tetrahydropyranylmethyl)benzylamine; THP-protected benzylamine; 4-(Benzylaminomethyl)tetrahydropyran
EINECS	Contact for details

Quality Control

Our n-(4-Tetrahydropyranylmethyl)Benzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.