Description

Isogambogenic Acid CAS NO 887923-47-9 is a bioactive natural compound belonging to the class of caged polyprenylated xanthones. This compound matters for its significant potential in pharmaceutical research and development, particularly as a lead structure for novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical companies, and biotechnology firms engaged in drug discovery, medicinal chemistry, and the study of natural product pharmacology.

Application

• Pharmaceutical R&D: Serves as a key intermediate or reference standard in the discovery and development of new anticancer and anti-inflammatory drugs.
• Medicinal Chemistry Studies: Used for structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties.
• Biological Screening: Employed as a test compound in high-throughput screening assays to identify novel biological targets and mechanisms of action.
• Analytical Reference Standard: Utilized in HPLC, LC-MS, and NMR for the qualitative and quantitative analysis of complex natural product extracts.
• Academic Research: Applied in university and institutional labs for fundamental research on natural product biosynthesis, isolation, and bioactivity.
• Preclinical Studies: Investigated in vitro and in vivo models to evaluate efficacy, toxicity, and pharmacodynamics.

Basic Information

Product Name	Isogambogenic Acid
CAS No.	887923-47-9
Molecular Formula	C₃₈H₄₆O₈
Molecular Weight	630.77 g/mol
Synonyms	Isogambogenic Acid; (1S,3aR,4S,5aR,5bS,9S,11aR,13aR,13bR)-9-(3-Furanyl)-4,5a,5b,8,8,11a,13b-heptamethyl-1-(1-methylethenyl)-2,3,3a,4,5,5a,5b,6,7,9,10,11,11a,12,13,13a,13b,14,15,15a,15b-icosahydro-1H-cyclopenta[7,8]phenanthro[2,1-d]oxepine-3,4,7,10,13-pentol; Gambogenic acid isomer; Garcinia xanthone derivative
EINECS	Contact for details

Quality Control

Our Isogambogenic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation, NMR and MS for structural verification, and tests for residual solvents and heavy metals where applicable. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Specifications can be tailored to meet specific project requirements upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. The material is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided. Keep the container in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Loss on Drying	≤ 2.0%
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.