Description

2-Bromo-4-Trifluoromethyl-Benzyl-Hydrazine is a high-value, multi-functional aromatic hydrazine derivative. This compound serves as a critical advanced pharmaceutical intermediate and versatile organic synthesis building block, prized for its unique trifluoromethyl and bromine substituents. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries to introduce key structural motifs into target molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing trifluoromethyl and hydrazine pharmacophores.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and insecticides where the bromine and CF3 groups enhance biological activity and stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Heterocyclic Chemistry: Essential starting material for constructing nitrogen-containing heterocycles like pyrazoles, triazoles, and indazoles via cyclization reactions.
• Material Science Research: Intermediate in the synthesis of functionalized aromatic compounds for advanced polymers and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke synthesis projects requiring precise, high-purity functionalization.

Basic Information

Item	Details
Product Name	2-Bromo-4-Trifluoromethyl-Benzyl-Hydrazine
CAS No.	887596-24-9
Molecular Formula	C8H8BrF3N2
Molecular Weight	269.06 g/mol
Synonyms	1-[(2-Bromo-4-(trifluoromethyl)phenyl)]methyl]hydrazine; (2-Bromo-4-(trifluoromethyl)benzyl)hydrazine; 2-Bromo-α-(trifluoromethyl)benzylhydrazine; 2-Bromo-4-(trifluoromethyl)benzenemethanamine, N-amine; 2-Bromo-4-trifluoromethylbenzyl hydrazine; α-Hydrazino-2-bromo-α-(trifluoromethyl)toluene; 1-(2-Bromo-4-trifluoromethyl-benzyl)-hydrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Trifluoromethyl-Benzyl-Hydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent batch-to-batch quality suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.