Description

2-Trifluoromethoxy-Benzyl-Hydrazine CAS NO 887595-82-6 is a high-purity, functionalized hydrazine derivative featuring a benzyl group substituted with a trifluoromethoxy moiety. This compound is a critical pharmaceutical intermediate and organic building block valued for its unique reactivity and the physicochemical properties imparted by the fluorine atoms. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Organic Synthesis & Research: Versatile reagent for constructing nitrogen-containing heterocycles (e.g., pyrazoles, indazoles) and for introducing the hydrazine functional group in complex molecule assembly.
• Material Science: Potential monomer or cross-linking agent in the development of specialty polymers and advanced materials with tailored properties.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Trifluoromethoxy-Benzyl-Hydrazine
CAS No.	887595-82-6
Molecular Formula	C8H9F3N2O
Molecular Weight	206.17 g/mol
Synonyms	1-[(2-Trifluoromethoxy)phenyl]methyl]hydrazine; (2-(Trifluoromethoxy)phenyl)methanamine, N-amino-; 2-(Trifluoromethoxy)benzylhydrazine; α-Hydrazino-2-(trifluoromethoxy)toluene; 1-(2-Trifluoromethoxybenzyl)hydrazine; 2-Trifluoromethoxybenzyl Hydrazine; (2-Trifluoromethoxybenzyl)hydrazine; 2-(Trifluoromethoxy)benzyl Hydrazine
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethoxy-Benzyl-Hydrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO compliant production for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.