Description

3-(3-Chlorophenyl)-4-Triisopropyl Silyloxy-Benzaldehyde is a high-value, protected aldehyde intermediate featuring a chlorophenyl group and a triisopropylsilyl (TIPS) ether protecting group. This compound matters for its role as a critical building block in advanced organic synthesis, where the TIPS group provides steric bulk and stability for selective reactions. Pharmaceutical, agrochemical, and advanced materials researchers need this chemical for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty chemicals where precise functional group manipulation is required.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides.
• Advanced Material Precursor: Serves as a monomer or intermediate in the production of specialty polymers and functional materials.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki or Heck reactions, due to its reactive aldehyde functionality.
• Ligand and Catalyst Development: Useful for constructing complex organic ligands used in asymmetric catalysis.
• Chemical Research & Development: A versatile intermediate for academic and industrial R&D in medicinal and synthetic chemistry.

Basic Information

Product Name	3-(3-Chlorophenyl)-4-Triisopropyl Silyloxy-Benzaldehyde
CAS No.	887407-78-5
Molecular Formula	C22H29ClO2Si
Molecular Weight	388.99 g/mol
Synonyms	4-[(Triisopropylsilyl)oxy]-3-(3-chlorophenyl)benzaldehyde; 3-(3-Chlorophenyl)-4-[(triisopropylsilyl)oxy]benzaldehyde; Benzaldehyde, 3-(3-chlorophenyl)-4-[(triisopropylsilyl)oxy]-; 3-(3-Chlorophenyl)-4-TIPS-Oxy-Benzaldehyde; 4-Triisopropylsilyloxy-3-(3-chlorophenyl)benzaldehyde; TIPS-protected 3-chlorophenyl benzaldehyde derivative; 3-Cl-Ph-4-OTIPS-Benzaldehyde
EINECS	Contact for details

Quality Control

Our 3-(3-Chlorophenyl)-4-Triisopropyl Silyloxy-Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment supports applications requiring reliable and reproducible performance in critical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and easily oxidized; for long-term storage, it is recommended to keep the container under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.