Description

4-(Chloromethyl)Benzyl Methanethiosulfonate is a specialized organosulfur compound featuring both a chloromethyl and a methanethiosulfonate functional group. This unique bifunctional structure makes it a valuable intermediate for the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting cysteine residues in proteins.
• Bioconjugation Reagent: Used in the modification of proteins, peptides, and antibodies for research, diagnostics, and therapeutic applications.
• Agrochemical Synthesis: Intermediate in the production of advanced pesticides and herbicides with specific modes of action.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.
• Chemical Biology Probes: Utilized to develop activity-based probes for studying enzyme function and metabolic pathways.
• Material Science: Precursor for surface functionalization and the creation of self-assembled monolayers (SAMs) on various substrates.

Basic Information

Product Name	4-(Chloromethyl)Benzyl Methanethiosulfonate
CAS No.	887354-05-4
Molecular Formula	C9H11ClO2S2
Molecular Weight	250.77 g/mol
Synonyms	4-(Chloromethyl)benzyl methanesulfonothioate; (4-(Chloromethyl)phenyl)methyl methanethiosulfonate; Benzyl 4-(chloromethyl) methanethiosulfonate; p-(Chloromethyl)benzyl methanethiosulfonate; MTS reagent derivative; Thiol-reactive chloromethyl compound
EINECS	Contact for details

Quality Control

Our 4-(Chloromethyl)Benzyl Methanethiosulfonate is produced under strict quality management protocols. Each batch is characterized and tested to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee reliable performance in your synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.