Description

6,7-Difluoro-Chroman-4-Ylamine is a fluorinated chroman derivative amine, a high-value pharmaceutical intermediate and building block in organic synthesis. Its core value lies in its unique molecular scaffold, which is critical for modulating the biological activity and physicochemical properties of target compounds. This specialty chemical is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the difluoro-chroman structure can enhance bioavailability and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor or chiral auxiliary in asymmetric synthesis and catalysis for producing enantiomerically pure compounds.
• Material Science: Employed in the research of advanced organic materials, such as liquid crystals or organic semiconductors, due to its rigid, fluorinated structure.
• Chemical Biology Probes: Utilized as a scaffold for designing fluorescent probes or molecular tags to study biological processes.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	6,7-Difluoro-Chroman-4-Ylamine
CAS No.	886762-82-9
Molecular Formula	C9H9F2NO
Molecular Weight	185.17 g/mol
Synonyms	6,7-Difluoro-4-chromanamine; 4-Amino-6,7-difluorochroman; 6,7-Difluoro-3,4-dihydro-2H-1-benzopyran-4-amine; 6,7-Difluoro-2,3-dihydro-4H-chromen-4-amine; 6,7-Difluoro-4-aminochroman; Chroman-4-amine, 6,7-difluoro-; 886762-82-9
EINECS	Contact for details

Quality Control

Our 6,7-Difluoro-Chroman-4-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for each lot to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.