Description

Pentafluorophenyl 3-Fluoro-Benzenesulfonate is a high-purity, specialty fluorinated sulfonate ester used as a key reagent in advanced organic synthesis. This compound is valued for its exceptional reactivity as an activating agent and its utility in constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and advanced materials sectors for applications requiring precise functional group manipulation.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for introducing sulfonate ester groups in the development of active pharmaceutical ingredients (APIs), especially in kinase inhibitor and antiviral drug candidates.
• Agrochemical Research: Used in the synthesis of novel fluorinated herbicides, fungicides, and plant growth regulators, leveraging the stability and bioactivity imparted by the pentafluorophenyl moiety.
• Polymer & Material Science: Serves as a monomer or cross-linking agent in the production of specialty fluoropolymers and high-performance materials with enhanced thermal and chemical resistance.
• Peptide & Protein Chemistry: Employed as an activating reagent for sulfonation reactions in peptide modification and bioconjugation strategies.
• Ligand & Catalyst Development: Utilized in the preparation of sophisticated ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.
• Chemical Biology Probes: Acts as a key synthetic handle for creating fluorinated probes and tags used in imaging and diagnostic assay development.

Basic Information

Product Name	Pentafluorophenyl 3-Fluoro-Benzenesulfonate
CAS No.	886503-30-6
Molecular Formula	C12H4F6O3S
Molecular Weight	342.21 g/mol
Synonyms	3-Fluorobenzenesulfonic Acid Pentafluorophenyl Ester; Pentafluorophenyl 3-Fluorobenzenesulfonate; 3-Fluorophenylsulfonyl Pentafluorobenzene; 1-Fluoro-3-[(pentafluorophenoxy)sulfonyl]benzene; NSC 886503; 886503-30-6; Pentafluorophenyl m-Fluorobenzenesulfonate
EINECS	Contact for details

Quality Control

Our Pentafluorophenyl 3-Fluoro-Benzenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.