Description

3-Chloro-1,1,1-Trifluoro-Pentane-2,4-Dione is a specialized fluorinated β-diketone building block, identified by CAS number 886502-58-5. This compound is valued for its unique reactivity profile, offering a versatile trifluoromethylated and chlorinated backbone for advanced chemical synthesis. It is primarily sought by R&D and production chemists in the pharmaceutical and agrochemical sectors for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl or β-diketone motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance lipophilicity and biological activity.
• Ligand Precursor: Serves as a starting material for the synthesis of chelating agents and metal-organic frameworks (MOFs) in materials science and catalysis.
• Fluorinated Polymer Research: Employed as a monomer or modifier in the development of specialty polymers with enhanced chemical resistance, thermal stability, or unique surface properties.
• Organic Synthesis Building Block: Utilized in various name reactions (e.g., Claisen condensations, Michael additions) to introduce functional complexity into target molecules.

Basic Information

Product Name	3-Chloro-1,1,1-Trifluoro-Pentane-2,4-Dione
CAS No.	886502-58-5
Molecular Formula	C5H4ClF3O2
Molecular Weight	188.53 g/mol
Synonyms	3-Chloro-1,1,1-trifluoropentane-2,4-dione; 3-Chloro-1,1,1-trifluoro-2,4-pentanedione; 1,1,1-Trifluoro-3-chloropentane-2,4-dione; 3-Chloro-1,1,1-trifluoroacetylacetone; 3-Chloropentafluoroacetylacetone; CF3COCH2COCH2Cl (common structural shorthand); Chlorotrifluoroacetylacetone
EINECS	Contact for details

Quality Control

Our 3-Chloro-1,1,1-Trifluoro-Pentane-2,4-Dione is manufactured under a strict quality management system. Each batch is analyzed to ensure high purity and consistency, with specifications typically covering identity, assay, and impurity profiles via modern analytical techniques. Certificates of Analysis (COA) are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.