Description

2-Chloro-6-(Trifluoromethyl)Benzyl Bromide is a high-value halogenated benzyl bromide derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and trifluoromethyl substituents, makes it an essential reagent for introducing functionalized benzyl groups into target molecules. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in creating advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functional monomers and specialty polymers for advanced materials.
• Cross-Coupling Reactions: Acts as an electrophile in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleophilic Substitution: The reactive benzyl bromide moiety allows for efficient functionalization with various nucleophiles.

Basic Information

Product Name	2-Chloro-6-(Trifluoromethyl)Benzyl Bromide
CAS No.	886500-26-1
Molecular Formula	C8H5BrClF3
Molecular Weight	273.48 g/mol
Synonyms	1-(Bromomethyl)-2-chloro-6-(trifluoromethyl)benzene; α-Bromo-2-chloro-α,α,α-trifluoro-o-xylene; (2-Chloro-6-(trifluoromethyl)phenyl)methyl bromide; 2-Chloro-α-(bromomethyl)benzotrifluoride; o-Chloro-α-bromobenzyl trifluoride
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.