Description

2-Chloro-6-Fluoro-3-Methoxybenzyl Bromide is a high-value, multi-functional benzyl bromide derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and methoxylated structure makes it an indispensable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the halogen and methoxy groups contribute to biological activity and selectivity.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and polymers requiring specific halogenated aromatic units.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.
• Academic and Industrial R&D: Fundamental building block in medicinal chemistry programs for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	2-Chloro-6-Fluoro-3-Methoxybenzyl Bromide
CAS No.	886499-54-3
Molecular Formula	C8H7BrClFO
Molecular Weight	268.50 g/mol
Synonyms	1-(Bromomethyl)-2-chloro-6-fluoro-3-methoxybenzene; (2-Chloro-6-fluoro-3-methoxyphenyl)methyl Bromide; 2-Chloro-6-fluoro-3-methoxybenzyl Bromide; Benzene, 1-(bromomethyl)-2-chloro-6-fluoro-3-methoxy-; α-Bromo-2-chloro-6-fluoro-3-methoxytoluene
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Fluoro-3-Methoxybenzyl Bromide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific customer requirements, including research-grade and development-scale quantities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.