Description

3-Chloro-n-(4-Trifluoromethoxy-Phenyl)-Propionamide is a specialized organic compound featuring a propionamide backbone substituted with a chloro group and a trifluoromethoxy-phenyl moiety. This unique molecular structure makes it a valuable high-purity intermediate in advanced synthetic chemistry, particularly for constructing complex molecules with specific electronic and steric properties. It is primarily sought after by pharmaceutical R&D and agrochemical laboratories for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Agrochemical Research: Used in the development of next-generation herbicides and fungicides, leveraging the stability imparted by the trifluoromethoxy group.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers with enhanced chemical resistance.
• Organic Synthesis Reagent: Employed in academic and industrial research for constructing complex amide and aryl ether derivatives.
• Ligand Synthesis: Potential precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-Chloro-n-(4-Trifluoromethoxy-Phenyl)-Propionamide
CAS No.	886498-78-8
Molecular Formula	C10H9ClF3NO2
Molecular Weight	267.63 g/mol
Synonyms	3-Chloro-N-[4-(trifluoromethoxy)phenyl]propanamide; 3-Chloro-N-(4-trifluoromethoxyphenyl)propionamide; N-(4-Trifluoromethoxyphenyl)-3-chloropropionamide; 3-Chloro-1-oxo-1-(4-(trifluoromethoxy)phenylamino)propane; Propionamide, 3-chloro-N-[4-(trifluoromethoxy)phenyl]-; 886498-78-8; 3-Chloro-N-(4-trifluoromethoxy-phenyl)-propionamide
EINECS	Contact for details

Quality Control

Our 3-Chloro-n-(4-Trifluoromethoxy-Phenyl)-Propionamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.