Description

3-Chloro-2-Fluorobenzylmethylsulfone is a high-purity fluorinated and chlorinated benzyl sulfone derivative, serving as a critical advanced intermediate in modern organic synthesis. Its unique structure, featuring both halogen substituents and a sulfone functional group, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the sulfone and halogen groups contribute to biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced materials with specific electronic or surface properties.
• Ligand and Catalyst Development: Employed in organometallic chemistry for the synthesis of novel ligands and catalysts used in cross-coupling and other transition metal-mediated reactions.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes for studying enzyme function and protein interactions within biological systems.

Basic Information

Product Name	3-Chloro-2-Fluorobenzylmethylsulfone
CAS No.	886498-11-9
Molecular Formula	C8H8ClFO2S
Molecular Weight	222.66 g/mol
Synonyms	1-(Chloro-3-fluoro-2-phenyl)methanesulfonylmethane; (3-Chloro-2-fluorophenyl)methyl methyl sulfone; Methyl (3-chloro-2-fluorobenzyl) sulfone; 3-Chloro-2-fluoro-α-(methylsulfonyl)toluene; 886498-11-9; 3-Chloro-2-fluorobenzyl methyl sulphone
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-2-Fluorobenzylmethylsulfone is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your research and development processes. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.