Description

2-Chloro-1-Cyclopropyl-4,4,4-Trifluoro-Butane-1,3-Dione is a specialized fluorinated diketone building block of significant interest in advanced organic synthesis. Its unique structure, featuring a reactive 1,3-dione moiety and a cyclopropyl ring, makes it a versatile precursor for constructing complex heterocyclic and fluorinated compounds. This high-value intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, particularly in medicinal chemistry programs targeting new therapeutic agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl and cyclopropyl groups can enhance biological activity and stability.
• Organic Synthesis Building Block: Serves as a versatile precursor for synthesizing complex heterocycles, such as pyrazoles and isoxazoles, via reactions with hydrazines or hydroxylamines.
• Material Science Research: Investigated for the preparation of fluorinated organic materials and ligands for metal-organic frameworks (MOFs) due to its specific electronic properties.
• Chemical Research & Development: Employed in academic and industrial R&D labs for methodology development and exploring new reaction pathways involving fluorinated enolates.

Basic Information

Product Name	2-Chloro-1-Cyclopropyl-4,4,4-Trifluoro-Butane-1,3-Dione
CAS No.	886494-04-8
Molecular Formula	C7H6ClF3O2
Molecular Weight	214.57 g/mol
Synonyms	2-Chloro-1-cyclopropyl-4,4,4-trifluorobutane-1,3-dione; 2-Chloro-1-cyclopropyl-4,4,4-trifluoro-1,3-butanedione; 1,3-Butanedione, 2-chloro-1-cyclopropyl-4,4,4-trifluoro-; 886494-04-8; 2-Chloro-1-cyclopropyl-4,4,4-trifluoro-β-diketone; Cyclopropyl 2-chloro-4,4,4-trifluoroacetoacetate precursor
EINECS	Contact for details

Quality Control

Our 2-Chloro-1-Cyclopropyl-4,4,4-Trifluoro-Butane-1,3-Dione is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The compound is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.