Description

4-Cbz-3-(Aminomethyl)Morpholine is a high-purity, protected morpholine derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise, reliable intermediates for constructing complex molecular architectures. It is primarily utilized in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Peptidomimetic Chemistry: Used to introduce constrained morpholine scaffolds into peptide backbones to enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a versatile building block for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Research: Intermediate in the development of new herbicides, fungicides, and insecticides with improved efficacy.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up production under cGMP conditions.

Basic Information

Product Name	4-Cbz-3-(Aminomethyl)Morpholine
CAS No.	886363-09-3
Molecular Formula	C13H18N2O3
Molecular Weight	250.30 g/mol
Synonyms	3-(Aminomethyl)-4-(benzyloxycarbonyl)morpholine; 4-(Benzyloxycarbonyl)-3-(aminomethyl)morpholine; N-Cbz-3-(aminomethyl)morpholine; 4-Carbobenzoxy-3-(aminomethyl)morpholine; 886363-09-3; Morpholine, 3-(aminomethyl)-4-[(phenylmethoxy)carbonyl]-; Benzyl 3-(aminomethyl)morpholine-4-carboxylate
EINECS	Contact for details

Quality Control

Our 4-Cbz-3-(Aminomethyl)Morpholine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can provide material tailored to specific project requirements, including cGMP-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.