Description

3-Boc-Aminomethylbenzamidine is a high-purity, protected benzamidine derivative used as a critical building block in organic synthesis and pharmaceutical research. Its value lies in its role as a key intermediate for the development of protease inhibitors and other biologically active molecules, enabling precise chemical modifications. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly serine protease inhibitors.
• Biochemical Research: Used as a precursor for labeled probes or activity-based protein profiling (ABPP) reagents.
• Peptidomimetic Chemistry: Serves as a building block for constructing peptide analogs and mimetics with enhanced stability.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize lead compounds.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs producing specialized fine chemicals.
• Chemical Biology Tool Development: Utilized to create inhibitors for studying enzymatic pathways and cellular processes.

Basic Information

Product Name	3-Boc-Aminomethylbenzamidine
CAS No.	886362-52-3
Molecular Formula	C13H19N3O2
Molecular Weight	249.31 g/mol
Synonyms	tert-Butyl N-[(3-carbamimidoylphenyl)methyl]carbamate; 3-[[(tert-Butoxycarbonyl)amino]methyl]benzamidine; 3-(Boc-aminomethyl)benzamidine; N-Boc-3-aminomethylbenzamidine; 3-(N-Boc-aminomethyl)benzamidine; Benzamidine, N-[3-(aminomethyl)phenyl]-carbamic acid 1,1-dimethylethyl ester; (3-Carbamimidoyl-benzyl)-carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 3-Boc-Aminomethylbenzamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability. Keep container tightly sealed in a desiccated environment when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.