Description

2,3-Difluoro-Benzamidine is a high-purity, functionalized benzamidine derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key precursor in the development of pharmaceutical intermediates, particularly for protease inhibitors and other biologically active molecules. Chemical manufacturers and R&D laboratories in the pharmaceutical, agrochemical, and material science sectors need this high-quality intermediate to drive innovation in their synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial synthon for the synthesis of novel drug candidates, especially protease inhibitors and enzyme modulators.
• Agrochemical Research: Used in developing new active ingredients for crop protection products, leveraging the fluorine atoms for enhanced bioactivity and stability.
• Chemical Synthesis Building Block: Serves as a versatile amidine precursor for constructing complex heterocycles and functionalized aromatic systems in medicinal chemistry.
• Material Science Precursor: Potential use in the synthesis of specialty polymers and advanced organic materials requiring fluorine-containing aromatic units.
• Biochemical Tool Compound: Can be utilized in research to study enzyme kinetics and inhibition mechanisms due to its amidine functional group.

Basic Information

Product Name	2,3-Difluoro-Benzamidine
CAS No.	885957-09-5
Molecular Formula	C7H6F2N2
Molecular Weight	156.13 g/mol
Synonyms	2,3-Difluorobenzene carboximidamide; 2,3-Difluorobenzamidine; Benzenecarboximidamide, 2,3-difluoro-; 2,3-Difluoro-benzenecarboximidamide; (2,3-Difluorophenyl)methanimidamide
EINECS	Contact for details

Quality Control

Our 2,3-Difluoro-Benzamidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.