Description

2,3,4,5,6-Pentafluorophenyl (3-Chlorophenyl)Methanesulfonate is a specialized organofluorine building block and sulfonate ester of significant interest in advanced synthetic chemistry. Its value lies in its dual functionality, serving as a versatile intermediate for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, structurally precise intermediates for coupling and derivatization reactions.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, especially those requiring fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides where the pentafluorophenyl and chlorophenyl groups impart specific biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of monomers and polymers for specialty materials, such as fluorinated polyarylates or liquid crystals.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and labeling reagents that target specific biological pathways.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl systems.

Basic Information

Product Name	2,3,4,5,6-Pentafluorophenyl (3-Chlorophenyl)Methanesulfonate
CAS No.	885950-65-2
Molecular Formula	C13H6ClF5O3S
Molecular Weight	372.70 g/mol
Synonyms	(3-Chlorophenyl)methanesulfonic acid 2,3,4,5,6-pentafluorophenyl ester; Pentafluorophenyl 3-chlorobenzyl sulfonate; 3-Chlorobenzyl pentafluorophenyl sulfonate; (3-Chlorobenzyl)sulfonyl pentafluorobenzene; PFP-3-chlorobenzyl sulfonate; Pentafluorophenyl (3-chlorobenzyl)sulfonate; Methanesulfonic acid, (3-chlorophenyl)-, 2,3,4,5,6-pentafluorophenyl ester
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorophenyl (3-Chlorophenyl)Methanesulfonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light). For long-term storage, consider storage under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.