Description

2,3,4,5,6-Pentafluorophenyl 3-(Trifluoromethyl)Benzenesulphonate is a high-value, multi-fluorinated sulfonate ester, a key building block in advanced organic synthesis. Its structure makes it an exceptional electrophilic reagent for introducing the pentafluorophenylsulfonyl (Pfp) group, a versatile and highly reactive leaving group. This compound is critically important for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries who require precise functionalization and the development of novel fluorinated molecules.

Application

• Pharmaceutical Intermediate: A crucial reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating sulfonamide derivatives and other complex molecules via nucleophilic substitution reactions.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the introduction of fluorine atoms enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Polymer and Materials Science: Employed to create fluorinated monomers and polymers, imparting valuable properties such as chemical resistance, thermal stability, and low surface energy.
• Proteomics and Bioconjugation: Acts as a reactive handle for labeling peptides, proteins, and other biomolecules, facilitating studies in chemical biology and diagnostics.
• Organic Electronics: Used in the synthesis of charge-transport materials and emissive layers for OLEDs and other electronic devices due to the electron-withdrawing nature of the fluorinated groups.

Basic Information

Product Name	2,3,4,5,6-Pentafluorophenyl 3-(Trifluoromethyl)Benzenesulphonate
CAS No.	885950-36-7
Molecular Formula	C13H4F8O3S
Molecular Weight	392.22 g/mol
Synonyms	Pentafluorophenyl 3-(Trifluoromethyl)benzenesulfonate; 3-(Trifluoromethyl)benzenesulfonic Acid Pentafluorophenyl Ester; Pentafluorophenyl α,α,α-Trifluoro-m-toluenesulfonate; PFP-3-Trifluoromethylbenzenesulfonate; PFP-Tf Ester; 3-Trifluoromethylphenylsulfonyl Pentafluorophenyl Ester; Pentafluorophenyl m-(Trifluoromethyl)phenyl Sulfonate
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorophenyl 3-(Trifluoromethyl)Benzenesulphonate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥98% (by HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality management system is designed to meet the stringent requirements of our global B2B partners in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged manipulations to prevent decomposition. Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.