Description

2,3,4,5,6-Pentafluorophenyl 2-Fluorobenzenesulphonate is a specialized fluorinated sulfonate ester, a high-value building block in advanced organic synthesis. Its core value lies in its unique perfluorinated phenyl group, which acts as a superior leaving group, enabling efficient and selective reactions under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where the introduction of fluorinated motifs is critical for enhancing metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key reagent in the synthesis of complex drug candidates, especially for introducing sulfonate ester protecting groups or creating fluorinated analogs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where fluorination improves efficacy and environmental profile.
• Material Science: Serves as a monomer or cross-linking agent in the production of specialty polymers with enhanced chemical resistance and thermal stability.
• Ligand & Catalyst Development: Employed in the preparation of fluorinated ligands for catalysis, enabling novel reaction pathways in fine chemical manufacturing.
• Chemical Biology Probes: Useful for synthesizing activity-based probes and labeling reagents that study enzyme function and biological pathways.
• Custom Synthesis & Process R&D: A versatile tool for contract research organizations (CROs) and process development teams exploring new synthetic routes.

Basic Information

Product Name	2,3,4,5,6-Pentafluorophenyl 2-Fluorobenzenesulphonate
CAS No.	885950-35-6
Molecular Formula	C12H4F6O3S
Molecular Weight	342.22 g/mol
Synonyms	Pentafluorophenyl 2-Fluorobenzenesulfonate; 2-Fluorobenzenesulfonic Acid Pentafluorophenyl Ester; 2-Fluorophenylsulfonyl Pentafluorophenyl Ether; 2-Fluoro Benzenesulfonyl Pentafluorophenyl Ester; 2-Fluorobenzene-1-sulfonyl Pentafluorophenyl Ester; PFP 2-Fluorobenzenesulfonate; (2-Fluorophenyl)sulfonyl Pentafluorophenyl Ester
EINECS	Contact for details

Quality Control

Every batch of 2,3,4,5,6-Pentafluorophenyl 2-Fluorobenzenesulphonate is manufactured and tested under strict quality management protocols. We guarantee high-purity material suitable for demanding research and scale-up applications. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.