Description

2,3,4,5,6-Pentafluorophenyl 3-Methylbenzenesulfonate is a high-purity, specialized sulfonate ester derivative, serving as a critical building block and reagent in advanced synthetic chemistry. Its value lies in the unique reactivity of the pentafluorophenyl (PFP) leaving group, which facilitates efficient coupling reactions under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries, enabling the synthesis of complex molecules and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sulfonate ester groups or facilitating nucleophilic substitution reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its reactivity to create bioactive compounds.
• Polymer & Materials Science: Acts as a functional monomer or cross-linking agent in the production of specialty polymers, coatings, and advanced materials with tailored properties.
• Ligand & Catalyst Preparation: Employed in the synthesis of sophisticated ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Bioconjugation & Probe Development: Useful in biochemical research for labeling proteins, peptides, or other biomolecules due to its selective reactivity.
• Organic Synthesis Reagent: A versatile reagent for constructing carbon-heteroatom and carbon-carbon bonds in complex multi-step synthetic routes.

Basic Information

Product Name	2,3,4,5,6-Pentafluorophenyl 3-Methylbenzenesulfonate
CAS No.	885950-34-5
Molecular Formula	C13H7F5O3S
Molecular Weight	338.25 g/mol
Synonyms	Pentafluorophenyl 3-Methylbenzenesulfonate; Pentafluorophenyl Tosylate; 3-Methylbenzenesulfonic Acid Pentafluorophenyl Ester; PFP Tosylate; Pentafluorophenyl p-Toluenesulfonate; 2,3,4,5,6-Pentafluorophenyl Tosylate; PFP-OTs; (2,3,4,5,6-Pentafluorophenyl) 3-Methylbenzene-1-sulfonate
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorophenyl 3-Methylbenzenesulfonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.