Description

2,3,4,5,6-Pentafluorophenyl 4-Cyanobenzenesulfonate is a high-purity, specialized sulfonate ester derivative designed for advanced synthetic chemistry applications. This compound serves as a critical building block and activating agent in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences and fine chemical industries for constructing novel chemical entities and developing new synthetic methodologies.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), especially for introducing sulfonate ester functionalities.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides requiring fluorinated aromatic components.
• Material Science Research: Building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to form biaryl systems.
• Proteomics & Bioconjugation: Potential use in labeling reagents and chemical probes for studying biological systems.
• Organic Synthesis: Versatile reagent for nucleophilic substitution reactions, leveraging the excellent leaving group ability of the pentafluorophenolate moiety.

Basic Information

Product Name	2,3,4,5,6-Pentafluorophenyl 4-Cyanobenzenesulfonate
CAS No.	885949-56-4
Molecular Formula	C13H5F5NO3S
Molecular Weight	365.25 g/mol
Synonyms	4-Cyanobenzenesulfonic Acid 2,3,4,5,6-Pentafluorophenyl Ester; Pentafluorophenyl 4-Cyanobenzenesulfonate; 4-Cyanophenylsulfonyl Pentafluorophenyl Ester; 4-Cyanobenzenesulfonyl Pentafluorophenyl Ester; Benzenesulfonic Acid, 4-cyano-, 2,3,4,5,6-pentafluorophenyl ester; PFP 4-Cyanobenzenesulfonate
EINECS	Contact for details

Quality Control

Our 2,3,4,5,6-Pentafluorophenyl 4-Cyanobenzenesulfonate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.