Description

(R)-(Tetrahydro-2H-Pyran-2-Yl)Methanamine Hydrochloride is a high-purity chiral amine building block essential for advanced organic synthesis. This compound matters as a key intermediate in the development of active pharmaceutical ingredients (APIs) and fine chemicals, where its defined stereochemistry is critical for biological activity. It is needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Catalysis Ligand Precursor: Used in the preparation of chiral ligands and organocatalysts for enantioselective transformations.
• Agrochemical Synthesis: Serves as a building block for creating chiral active ingredients in herbicides, fungicides, and insecticides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Process R&D: A valuable reagent for method development and scaling chiral synthetic routes in laboratory and pilot plant settings.

Basic Information

Product Name	(R)-(Tetrahydro-2H-Pyran-2-Yl)Methanamine Hydrochloride
CAS No.	885331-26-0
Molecular Formula	C6H14ClNO
Molecular Weight	151.64 g/mol
Synonyms	(R)-1-(Tetrahydro-2H-pyran-2-yl)methanamine hydrochloride; (R)-THPMA-HCl; (R)-Aminomethyltetrahydropyran hydrochloride; (R)-2-(Aminomethyl)tetrahydro-2H-pyran hydrochloride; (R)-Tetrahydro-2H-pyran-2-ylmethanamine hydrochloride; (R)-2-Pyranmethanamine, tetrahydro-, hydrochloride; (R)-Tetrahydropyran-2-ylmethylamine hydrochloride
EINECS	Contact for details

Quality Control

Our (R)-(Tetrahydro-2H-Pyran-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.