Description

4-(1H-Indol-6-Yl)-Tetrahydro-Pyran-4-Ol CAS NO 885273-47-2 is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines indole and tetrahydropyran motifs. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel bioactive molecules. It is primarily sought after by pharmaceutical companies, biotechnology research firms, and contract research organizations (CROs) engaged in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, particularly those with complex heterocyclic architectures.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• CNS Drug Development: Employed in the research of compounds targeting neurological pathways, given the pharmacological relevance of the indole core.
• Oncological Research: Serves as a building block for developing small-molecule inhibitors and other therapeutic agents in cancer research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
• Academic Research: Utilized in university and institutional labs for organic synthesis methodology development and biochemical studies.

Basic Information

Product Name	4-(1H-Indol-6-Yl)-Tetrahydro-Pyran-4-Ol
CAS No.	885273-47-2
Molecular Formula	C₁₃H₁₅NO₂
Molecular Weight	217.26 g/mol
Synonyms	4-(1H-Indol-6-yl)oxan-4-ol; 4-(6-Indolyl)-4-hydroxytetrahydropyran; 4-(1H-Indol-6-yl)tetrahydro-2H-pyran-4-ol; Tetrahydro-4-(1H-indol-6-yl)-2H-pyran-4-ol; 4-(Indol-6-yl)-4-hydroxytetrahydropyran; 4-Hydroxy-4-(1H-indol-6-yl)tetrahydropyran; 885273-47-2
EINECS	Contact for details

Quality Control

Our 4-(1H-Indol-6-Yl)-Tetrahydro-Pyran-4-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications. Our quality commitment supports applications requiring high-purity intermediates for regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.