Description

4-(1H-Indol-5-Yl)-Tetrahydro-Pyran-4-Ol CAS NO 885273-22-3 is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular scaffold that combines indole and tetrahydropyran motifs. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for synthesizing novel bioactive molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating new drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and oncology drug discovery programs.
• Medicinal Chemistry Building Block: Used to construct complex molecular architectures for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Research: Serves as a precursor in the synthesis of novel pesticides and herbicides with potential new modes of action.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialty chemicals, dyes, and functional materials.
• Academic & Contract Research: Utilized in university laboratories and CROs (Contract Research Organizations) for exploratory chemical synthesis and methodology development.

Basic Information

Product Name	4-(1H-Indol-5-Yl)-Tetrahydro-Pyran-4-Ol
CAS No.	885273-22-3
Molecular Formula	C₁₄H₁₇NO₂
Molecular Weight	231.29 g/mol
Synonyms	4-(1H-Indol-5-yl)oxan-4-ol; 4-(1H-Indol-5-yl)tetrahydro-2H-pyran-4-ol; 4-(5-Indolyl)-4-hydroxytetrahydropyran; Tetrahydro-4-(5-indolyl)-4-pyranol; 4-Hydroxy-4-(5-indolyl)tetrahydropyran; 4-(1H-Indol-5-yl)tetrahydropyran-4-ol; 4-(5-Indolyl)-4-hydroxytetrahydropyran; 885273-22-3
EINECS	Contact for details

Quality Control

Every batch of 4-(1H-Indol-5-Yl)-Tetrahydro-Pyran-4-Ol is manufactured under a strict quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity specifications suitable for research and development. A comprehensive Certificate of Analysis (COA) detailing purity (typically by HPLC), identity (by IR, NMR), and impurity profile is provided with each shipment. Custom synthesis and purification to meet specific client requirements (e.g., >98%, >99%) are available.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.