Description

5-(3,6-Dihydro-2H-Pyran-4-Yl)-1H-Indazole is a high-purity heterocyclic organic compound featuring a fused indazole and dihydropyran structure. This advanced pharmaceutical intermediate is critical for medicinal chemistry research and the development of novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for the synthesis of targeted small molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities targeting various biological pathways.
• Kinase Inhibitor Development: The indazole moiety makes it a valuable precursor in the development of potential kinase inhibitors for oncology and inflammatory diseases.
• Chemical Biology Probes: Employed in the creation of molecular probes to study enzyme function and cellular signaling mechanisms.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the efficient, scalable production of candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development programs for global clients.

Basic Information

Item	Details
Product Name	5-(3,6-Dihydro-2H-Pyran-4-Yl)-1H-Indazole
CAS No.	885272-68-4
Molecular Formula	C₁₂H₁₂N₂O
Molecular Weight	200.24 g/mol
Synonyms	5-(3,6-Dihydro-2H-pyran-4-yl)-1H-indazole; 5-(3,6-Dihydro-2H-pyran-4-yl)indazole; 4-(1H-Indazol-5-yl)-3,6-dihydro-2H-pyran; 885272-68-4; 5-(3,6-Dihydro-2H-pyran-4-yl)-1H-indazole; 5-(3,6-dihydro-2H-pyran-4-yl)-1H-indazole
EINECS	Contact for details

Quality Control

Our 5-(3,6-Dihydro-2H-Pyran-4-Yl)-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.