Description

(8-Bromo-6-Chloro-Chroman-3-Yl)-Methylamine is a high-purity, synthetically derived chroman derivative, a key building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of complex, biologically active molecules, offering precise functionalization for structure-activity relationship (SAR) studies. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries, as well as by fine chemical manufacturers specializing in custom synthesis and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Research: Used in the development of new active ingredients for crop protection and pest management.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical companies offering bespoke synthesis services.
• Academic & Institutional Research: Employed in university and R&D institute laboratories for methodological studies in heterocyclic chemistry.
• Material Science Exploration: Investigated as a potential monomer or additive for specialized polymeric materials.

Basic Information

Product Name	(8-Bromo-6-Chloro-Chroman-3-Yl)-Methylamine
CAS No.	885271-41-0
Molecular Formula	C10H11BrClNO
Molecular Weight	276.56 g/mol
Synonyms	1-(8-Bromo-6-chloro-3,4-dihydro-2H-chromen-3-yl)-N-methylmethanamine; 1-(8-Bromo-6-chloro-3,4-dihydro-2H-1-benzopyran-3-yl)-N-methylmethanamine; 8-Bromo-6-chloro-3-(methylaminomethyl)chroman; 3-(Aminomethyl)-8-bromo-6-chlorochroman; (8-Bromo-6-chloro-3,4-dihydro-2H-chromen-3-yl)methyl(methyl)amine
EINECS	Contact for details

Quality Control

Our (8-Bromo-6-Chloro-Chroman-3-Yl)-Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with cGMP and ICH guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.