Description

8-Bromo-6-Chloro-2H-Chromene-3-Carboxylic Acid Methyl Ester is a high-purity chromene derivative, a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized heterocyclic structure, which serves as a versatile building block for constructing complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. The CAS number for this specific compound is 885271-05-6.

Application

This specialized chromene ester is a key intermediate in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: Serves as a core scaffold for the development of new therapeutic agents, particularly in medicinal chemistry research for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the chromene structure can impart specific biological activity.
• Material Science Research: Acts as a precursor for the synthesis of advanced organic materials, including dyes, pigments, and functional polymers.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for method development and exploring new chemical reactions.
• Ligand and Catalyst Development: The functional groups present make it a candidate for constructing complex ligands used in catalytic systems.

Basic Information

Product Name	8-Bromo-6-Chloro-2H-Chromene-3-Carboxylic Acid Methyl Ester
CAS No.	885271-05-6
Molecular Formula	C11H8BrClO3
Molecular Weight	303.54 g/mol
Synonyms	Methyl 8-bromo-6-chloro-2H-chromene-3-carboxylate; 8-Bromo-6-chloro-2H-1-benzopyran-3-carboxylic acid methyl ester; 6-Chloro-8-bromo-2H-chromene-3-carboxylic acid methyl ester; 2H-1-Benzopyran-3-carboxylic acid, 8-bromo-6-chloro-, methyl ester; Chromene-3-carboxylic acid, 8-bromo-6-chloro-, methyl ester; CAS 885271-05-6
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Chloro-2H-Chromene-3-Carboxylic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes results from HPLC, NMR, and other relevant spectroscopic methods. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is between 2°C and 8°C. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.