Description

8-Bromo-6-Chloro-2H-Chromene-3-Carbaldehyde is a high-purity, functionalized chromene derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique halogenated structure makes it a valuable building block for constructing complex heterocyclic frameworks, particularly in pharmaceutical and agrochemical research. This compound is essential for medicinal chemists and R&D laboratories focused on developing novel active ingredients, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Used in the development of organic light-emitting diodes (OLEDs) and advanced photoresponsive materials.
• Chemical Biology: Serves as a probe or labeling agent in biochemical studies due to its reactive aldehyde group.
• Academic & Industrial R&D: Fundamental reagent for methodological studies in organic synthesis and heterocyclic chemistry.
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals, dyes, and complex fragrance molecules.

Basic Information

Product Name	8-Bromo-6-Chloro-2H-Chromene-3-Carbaldehyde
CAS No.	885271-03-4
Molecular Formula	C10H6BrClO2
Molecular Weight	273.51 g/mol
Synonyms	8-Bromo-6-chloro-2H-1-benzopyran-3-carboxaldehyde; 6-Chloro-8-bromo-2H-chromene-3-carbaldehyde; 8-Bromo-6-chloro-3-formyl-2H-chromene; 2H-1-Benzopyran-3-carboxaldehyde, 8-bromo-6-chloro-; 885271-03-4; 8-Br-6-Cl-2H-chromene-3-CHO
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Chloro-2H-Chromene-3-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.